Managing Side Effects of Saxenda: An Overview
Saxenda, a medication used for weight management, carries a significant warning about the potential risk of thyroid C-cell tumors and thyroid cancer. This warning, the FDA's strongest, is based on animal studies, although the risk in humans is still not definitively proven [1][5].
The drug belongs to the class of GLP-1 receptor agonists, a group of medications that have been linked with this thyroid safety concern. As a result, users of Saxenda are advised to have regular medical checkups and to report any adverse effects to their healthcare provider as early detection is crucial [1][5].
One of the most common side effects of Saxenda is nausea, which was the most common reason people stopped using it in its clinical trials. To manage this side effect, tips include avoiding fatty, fried, oily, spicy, or heavily seasoned foods, avoiding strong aromas and smells, eating several small snacks or meals during the day instead of three large meals, and taking small sips of water or sucking ice chips throughout the day [2].
Before starting Saxenda treatment, it's important to inform your doctor if you or a relative has had thyroid cancer or multiple endocrine neoplasia syndrome type 2. They can recommend other options for your weight management [2].
It's also worth noting that alcohol can cause many of the same side effects as Saxenda and can worsen these side effects during treatment. If you drink alcohol, talk with your doctor about it [2].
Saxenda may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. These include allergic reaction, depression or suicidal thoughts, gastroparesis, kidney problems, liver problems, type 2 diabetes, and pregnancy or breastfeeding [3].
If you have a personal or family history of thyroid tumors or cancer, your doctor will likely not prescribe Saxenda. It isn't known whether Saxenda is safe to use while breastfeeding. If you are breastfeeding or planning to breastfeed, talk with your doctor [3].
It isn't safe to use Saxenda during pregnancy. If you become pregnant during treatment, contact your doctor right away [3].
Saxenda can cause an allergic reaction in some people, although this side effect was rare in its clinical trials. Symptoms can include skin rash, itching, flushing, swelling under the skin, swelling of the mouth, tongue, or throat, and difficulty breathing [3].
If you'd like to learn more about Saxenda, talk with your doctor or pharmacist. They can help answer any questions you have about the drug's side effects [4].
In summary, Saxenda has a boxed warning about the increased risk of thyroid C-cell tumors. Long-term use may potentially lead to thyroid cancer as a serious adverse effect. Medical providers recommend monitoring thyroid health regularly during Saxenda treatment.
- Saxenda, a medication for weight management, carries a warning about the potential risk of thyroid C-cell tumors and thyroid cancer, which is based on animal studies, though the risk in humans isn't confirmed.
- Users of Saxenda are advised to have regular medical checkups due to the thyroid safety concern associated with this drug, and they should report any adverse effects to their healthcare provider promptly.
- One of the most common side effects of Saxenda is nausea, and tips to manage this include avoiding certain types of food, eating several small meals throughout the day, and staying hydrated.
- Before starting Saxenda treatment, it's essential to inform your doctor if you or a relative has had thyroid cancer or multiple endocrine neoplasia syndrome type 2, as other options for weight management may be recommended.
- Alcohol can cause similar side effects as Saxenda and may worsen these effects during treatment, so it's important to discuss alcohol use with your doctor before beginning treatment.
