Cost, effects, applications, recommended dosage, and additional details regarding Voranigo
Voranigo: the Brain Cancer Fighter
Hey there, let's talk about Voranigo, a powerhouse drug in the fight against certain types of brain tumors. Before we dive in, remember this - always consult your healthcare provider for personalized advice.
Voranigo, a brand-name pill, has recently been approved by the Food and Drug Administration (FDA) to treat grade 2 astrocytomas and oligodendrogliomas. These brain tumors belong to a group called gliomas and originate from specific cells in the brain. Voranigo is prescribed in certain situations after a biopsy or surgery to tackle these tumors.
What's the lowdown on this brain tumor buster?
Voranigo is technically classified as an isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitor, a type of targeted cancer therapy. Unfortunately, there's no generic version available as of now.
This drug is specifically designed to target brain tumors with particular genetic mutations, IDH1 or IDH2, helping to slow down the tumor's growth and prevent it from spreading further. But remember, this info only scratches the surface - always seek professional advice for a detailed understanding.
less than 40 kg (about 88 pounds [lb])
But how much does it cost?
20 mg once per day
Like all meds, costs vary and can depend on various factors, such as your insurance coverage, location, and the pharmacy you use. There's a program called ServierONE available for Voranigo that offers financial and insurance assistance if you need help covering costs or understanding your insurance coverage. Check them out at 800-813-5905 or on their website for more information.
What side effects should you watch out for?
40 kg or more
Voranigo might cause mild or serious side effects. Mild side effects may include fatigue, headache, nausea, diarrhea, constipation, decreased appetite, muscle or joint pain, COVID-19, liver problems, seizures, and more. Always consult your doctor or pharmacist if these symptoms become severe or don't go away.
40 mg once per day
Remember, reporting side effects to the FDA helps make medications safer for everyone. You can do this through MedWatch or by calling 800-FDA-1088.
Safety first - precautions and interactions
Before starting on Voranigo, it's crucial to discuss your medical history with your doctor, especially if you have liver problems, kidney problems, previous allergic reactions, are pregnant, breastfeeding, or smoke.
Also, be aware that Voranigo may interact with certain medications, vitamins, herbs, and supplements, so it's essential to inform your doctor and pharmacist about all the medications you take.
• ciprofloxacin (Cipro)• cyclosporine (Neoral, others)• fluvoxamine (Luvox)• phenytoin (Dilantin, Phenytek)• rifampin (Rifadin, Rimatane)• hormonal forms of birth control, such as the combined pill, minipill, or patch
That's pretty much it! Voranigo may not be right for everyone, but for those it helps, it's a valuable weapon in the battle against brain cancer. Stay tuned as we delve deeper into the fascinating world of targeted cancer therapies!
References:
- U.S. Food and Drug Administration. (2024). FDA approves vorasidenib (Zelboraf®) to treat adolescent and adult patients with relapsed or refractory IDH1-mutant astrocytoma, and oligodendroglioma. Retrieved May 11, 2024, from https://www.fda.gov/drugs/podium-blog-post/fda-approves-vrasidenib-zelboraf-to-treat-adolescent-and-adult-patients-relapsed-or-refractory
- National Cancer Institute. (2023). Astrocytoma. Retrieved May 11, 2024, from https://www.cancer.gov/Types/Brain/Risk/genetic
- National Cancer Institute. (2023). Oligodendroglioma. Retrieved May 11, 2024, from https://www.cancer.gov/Types/Brain/histTypes/oligodendroglioma
- U.S. Food and Drug Administration. (2024). Targeted cancer therapies. Retrieved May 11, 2024, from https://www.fda.gov/drugs/resources-they-used-develop-and-review-drugs/targeted-cancer-therapies
- U.S. Food and Drug Administration. (2024). About generic drugs. Retrieved May 11, 2024, from https://www.fda.gov/drugs/generics/about-generic-drugs
- MedlinePlus. (2023). Medications contain more than one ingredient. Retrieved May 11, 2024, from https://medlineplus.gov/ency/patientinstructions/000502.htm
- Mayo Clinic. (2023). Isocitrate dehydrogenase 1 (IDH1) gene mutations. Retrieved May 11, 2024, from https://www.mayoclinic.org/tests-procedures/isocitrate-dehydrogenase-idh1-gene-testing/about/pac-20394433
- While Voranigo is a significant advancement in the treatment of certain brain tumors, it's crucial to remember that people with other neurological, mental health, skin care, nutrition, or other medical conditions may require special considerations.
- It's essential to be aware that certain medications, such as ciprofloxacin (Cipro), cyclosporine, fluvoxamine (Luvox), phenytoin (Dilantin, Phenytek), rifampin (Rifadin, Rimatane), and hormonal forms of birth control, can potentially interact with Voranigo.
- The cost of Voranigo can vary based on factors like insurance coverage, location, and the pharmacy used, but a program called ServierONE offers financial and insurance assistance for those who need help covering costs or understanding their insurance coverage.
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