Biological markers shed light on daytime fatigue phenomenon
In a groundbreaking study published in Lancet BioMedicine in 2025, researchers Faquih and their team delved into the intricate world of steroid hormone biosynthesis and its connection to excessive daytime sleepiness.
The study revealed that certain diet-related metabolites play a significant role in the occurrence of excessive daytime sleepiness. Specifically, the researchers found that omega-3 and omega-6 fatty acids, commonly found in Mediterranean diet foods, are associated with a lower risk of excessive daytime sleepiness.
However, the search results do not provide specific information about who presented the study on the connection between these essential fatty acids and excessive daytime sleepiness.
On the flip side, the study also highlighted tyramine, a compound found in fermented and overripe foods, as a potential culprit for increased daytime sleepiness, particularly in men.
The researchers collected data on 877 metabolites from 6,000 participants and a questionnaire about daytime sleepiness. Seven metabolites were linked to excessive daytime sleepiness, and three more varied depending on gender.
Interestingly, metabolites such as progesterone, known for its role in sleep-related processes like melatonin production, were also found to be associated with excessive daytime sleepiness.
Another study, published in Nature, suggests that mitochondria may be the reason for the need to sleep due to their need for regular breaks for proper oxygen utilization.
The findings of these studies imply that maintaining a balanced diet rich in omega-3 and omega-6 fatty acids could potentially help reduce daytime fatigue. However, future approaches may include conducting clinical trials and tests in a sleep lab to examine the effects of these fatty acids on excessive daytime sleepiness more closely.
Furthermore, the researchers suggest that changing one's diet or taking supplements and medications may also help manage daytime sleepiness. It's worth noting that getting enough sleep is crucial for overall health, and those who don't get enough sleep have a higher risk of catching infections like a cold, according to a study published in Chronobiology International.
In conclusion, the research provides valuable insights into the relationship between diet and excessive daytime sleepiness. As more studies are conducted, we may uncover even more ways to combat this issue and improve our overall health and wellbeing.
