Becker Muscular Dystrophy: Symptoms, Progression, and DMD Comparison
Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy (DMD) are two common inherited muscle disorders. While both conditions affect males more often, BMD is less severe and less common than DMD. Here's an overview of BMD, its symptoms, progression, and comparison with DMD.
Muscular dystrophies cause progressive muscle tissue breakdown. BMD and DMD share symptoms like muscle weakness, joint and bone issues, heart and breathing problems. However, BMD symptoms typically appear later, from 5 years to 60 years, compared to DMD's onset at 2 to 3 years.
BMD progresses more slowly and unpredictably. Most people with BMD walk unassisted into their 40s or longer. Historically, life expectancy in BMD has been longer than DMD, with many living into mid to late adulthood. This is due to the partially functional dystrophin protein produced in BMD, unlike DMD where functional dystrophin is lost.
Each year, an estimated 400 to 600 boys are born with BMD or DMD in the US.
BMD, while progressive, has a later onset and slower progression than DMD. Its symptoms may appear anytime from childhood to adulthood, and life expectancy is generally longer. Both conditions are more common in males due to their single X chromosome. If you or someone you know shows signs of muscle weakness or other symptoms, consult a healthcare provider for proper evaluation and care.
